AI is transforming pharma.
Biology is the bottleneck.
Human biology meets predictive AI.
Quris combines functional human 3D tissue models with AI to investigate drug safety. Our platform generates experimental evidence and predictive insights to support pharmaceutical development decisions.
Validated with Pharma. Built for Real Development Decisions.
Quris collaborates with leading global pharmaceutical companies, including top-10 pharma partners. Our publicly announced relationship with Merck KGaA has progressed from blinded validation to commercial integration, while additional collaborations remain confidential.
Merck KGaA
Publicly announced collaboration
Additional Top-10 Pharma
Confidential collaborations
Validate
Blinded evaluation of predictive performance.
Apply
Drug-safety scanning and analysis.
Expand
Collaborative development of additional capabilities.
See How Drugs Affect Human Liver Function
Beyond Cell Viability
Quris measures functional, metabolic and injury-related responses in human 3D liver models. These complementary readouts help build a more complete picture of drug-induced liver effects.
Functional Human Liver Models
Measure drug effects in living human 3D liver tissue.
Dose- and Time-Dependent Responses
Track biological changes across concentrations and exposure periods.
Multiple Biological Readouts
Combine functional and injury-related measurements to investigate safety signals.
Drug Safety Across Therapeutic Modalities
Different therapeutic modalities raise different safety questions. Quris develops human-relevant experimental approaches tailored to the needs of each program.
Small Molecules
Investigate dose-dependent effects on human liver function and cellular health.
Biologics
Explore safety questions involving biological therapies and human tissue responses.
ADC Payloads
Assess payload-associated toxicity in human tissue models.
PROTACs
Investigate safety effects associated with targeted protein degradation.
Molecular Glues
Study emerging protein degraders using human-relevant experimental approaches.
Immune-Integrated Studies
Explore interactions between immune cells and human liver tissue.
Validation depth differs by modality. Liver safety is Quris's established commercial application; other assays are defined per program.
From Biological Data to Development Decisions
Quris delivers quantitative experimental results, AI-supported analysis and scientific interpretation through reports and interactive dashboards.
Quantitative Results
Explore concentration-response relationships and changes over time.
AI-Supported Analysis
Connect measured biological responses with predictive insights.
Interactive Dashboards
Review study results, visualizations and supporting data in one place.
Have a Drug Safety Question?
Explore how Quris can support your development program.